Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. We study 2,437 people who have Abdominal fullness prematurely after meals or Pityriasis rosea. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. doi: 10.1016/j.jaad.2020.04.094, 8. Peripheral eosinophilia is often present. 1. PRISMA flowchart. J Invest Dermatol. Manifestation of pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccine: A systematic review. 2023 The Authors. Typically preceded by a primary solitary herald patch followed by the onset of smaller scaly papulo-squamous lesions on the skin tension lines within days to weeks.1 Reactivation of herpes virus 6 and 7 has been incriminated as a . Reply to "the significance of investigating clinical, histopathologic and virological features in pityriasis rosea and pityriasis rosea-like eruptions following COVID-19 vaccinations" by Ciccarese G. et al. PRISMA, preferred reporting items for systematic reviews and metaanalysis. Keywords: Link Between COVID-19 and Skin Problems Identified - Medindia Martora F, Picone V, Battista T, Fabbrocini G, Marasca C. Dermatol Ther. Manifestation of pityriasis rosea and pityriasis rosea-like - PubMed 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. 2022 Jan;114:88-89. doi: 10.1016/j.ijid.2021.10.055. Careers. Please enable it to take advantage of the complete set of features! Numerous scattered erythematous plaques with fine scale oriented along skin cleavage, Herald patch of pityriasis rosea. The association between pityriasis rosea and pityriasis rosea-like eruptions after Covid-19 vaccines was established, but given the scarcity of studies, there is a need to conduct different clinical trials to confirm this association further and study the etiology and mechanism of the disease. 2021;185(2):e34. Here, we described a case of PR-like eruption that developed 14 days after Oxford/AstraZeneca vaccination in a 52-year-old Thai woman with glioblastoma. Some patients may have a cold before the rash. A 52-year-old Thai woman with a one-year history of recurrent glioblastoma was admitted to our hospital for a planned targeted therapy. Int J Dermatol. 2022 Aug;35(8):e15602. official website and that any information you provide is encrypted 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Disclaimer. Inclusion in an NLM database does not imply endorsement of, or agreement with, 2021;23(3):221228. It manifests as oval-shaped, pink or red . Immunity, Inflammation and Disease published by John Wiley & Sons Ltd. Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. 2022;S0738-081X(22)00002-5. Pityriasis rosea developing after COVID19 vaccination Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. MeSH eCollection 2022. Catal A, Muoz-Santos C, Galvn- Casas C, et al.. Cutaneous reactions after SARS-COV-2 vaccination: a crosssectional Spanish nationwide study of 405 cases, Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. The authors declare no conflict of interest. Would you like email updates of new search results? Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. It can take 1 to 3 months to go away. Please enable it to take advantage of the complete set of features! Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. Manifestation of pityriasis rosea and pityriasis rosea-like eruptions Careers. eCollection 2021. Of the 30 cases found, none experienced severe adverse effects and the rash resolved in an average of 5.6 weeks. Pityriasis versicolor is caused by a yeast infection and can be treated with antifungal medicines , including antifungal creams and antifungal shampoos. McMahon DE, Kovarik CL, Damsky W, et al.. Clinical and pathologic correlation of cutaneous COVID-19 vaccine reactions including V-REPP: a registry-based study. But there are important differences between these 2 conditions. eCollection 2023 Mar 7. Authors Lina Abdullah 1 Methods: Conflict of interest: The authors declare no potential conflict of interest. We originally reported patients with COVID-19 [2], Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. Only some cases of PR/pityriasis rosealike eruption (PRLE) after anti-SARS-CoV- 2 vaccination have been reported.1-18 In the period May 2021-February 2022 we observed five cases of clinically typical PR that appeared after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA-1273 (2 patients). Epub 2021 Aug 7. Pityriasis Rosea Treatment, Causes, Stages, Pictures & Herpes - MedicineNet There is a growing number of published cases that link PR to COVID-19 infection, with PR appearing either in the acute phase of COVID-19 or, as in our patient, in the post COVID-19 period (4-9). 2023 Mar 3;14(2):207-212. doi: 10.4103/idoj.idoj_449_22. (2020) 33:e13878. Availability of data and material: Data and materials are available by the authors. Patient n. 1. Dermatol Online J. PRISMA flowchart. Would you like email updates of new search results? The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Skin Diseases Associated With COVID-19: A Narrative Review He denied oropharyngeal lesions. 1. Viruses, Variants, and Vaccines: How COVID-19 Has Changed the Way We Look at Skin. official website and that any information you provide is encrypted doi: 10.1002/jmv.26549, 9. "Covid arm," a red, rashlike skin reaction that can occur at the injection site days after inoculation, has been well-publicized. Unlike in our patient, oropharyngeal lesions were observed in approximately 16% of patients with typical PR (10). (2017) 5:20311. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). The .gov means its official. Several vaccines have been created to counteract the morbidity and mortality associated with COVID19 and stop viral transmission, including the Moderna vaccine (Mrna1273).The mRNA1273 vaccine is a lipid nanoparticle-encapsulated mRNAbased vaccine that encodes the prefusion stabilized fulllength spike . official website and that any information you provide is encrypted Informed consent: Informed consent has been obtained. The site is secure. Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). This site needs JavaScript to work properly. With COVID-19 vaccines being authorized for emergency use, monitoring for potential adverse effects (e.g., cutaneous reactions) is necessary. The rash can be itchy. The https:// ensures that you are connecting to the The rash most often appears on the chest, back, and belly. An official website of the United States government. Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). PR has also been reported to follow COVID-19 vaccination (11). All patients are currently in good general health. 2023 Apr;11(4):e804. Bethesda, MD 20894, Web Policies Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. Globally, as of 7:26 pm CEST, 10 October 2022, there have been 618,521,620 confirmed cases of COVID-19, including 6,534,725 deaths, reported to the WHO. Suchonwanit P, Leerunyakul K, Kositkuljorn C. Cutaneous manifestations in COVID-19: Lessons learned from current evidence. Morphologic misclassication is possible. Factors affecting the severity of central centrifugal cicatricial alopecia. Received: 03 August 2021; Accepted: 17 August 2021; Published: 07 September 2021. Dermatology. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. The clinics of HHV-6 infection in COVID-19 pandemic: pityriasis rosea and Kawasaki disease. Unauthorized use of these marks is strictly prohibited. The latter is found in a younger age group. The patients/participants provided their written informed consent to participate in this study. Only a few cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. doi: 10.1111/bjd.20143. the reactivation of varicella zoster or herpes simplex infections, pityriasis rosea or rosea-like lesions, petechiae, pernicious purpura . J Eur Acad Dermatol Venereol. No HHV-6 and HHV-7 reactivation is detected. Apply a moisturizer, calamine lotion or a nonprescription . Petechial Skin Rash Associated With Severe Acute Respiratory - JAMA Dermatol Reports. Epub 2022 Mar 8. This site needs JavaScript to work properly. 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